Recombinant Human MSLN/Mesothelin(37-286) Protein(His Tag)种属来源分子量外观形态序列标签纯度内毒素水平溶解方法储存/保存方法背景说明Accession
| 概述 | |
| 种属 |
Human
|
| 来源 |
HEK293
|
| 分子量 |
30-33kDa (Reducing)
|
| 外观 |
Lyophilized powder
|
| 形态 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4
|
| 性能 | |
| 序列 |
Leu37-Arg286, with C-terminal 8*His
LAGETGQEAAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERHHHHHHHH |
| 标签 |
His Tag
|
| 纯度 |
>95% by SDS-PAGE&RP-HPLC
|
| 内毒素水平 |
<0.1EU/ug
|
| 溶解方法 |
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
|
| 储存/保存方法 |
Within 1 week, 2 to 8 °C under sterile conditions after reconstitution. 12 months from date of receipt, -20 to -80 °C as supplied. Avoid repeated freeze-thaw cycles.
|
| 靶标 | |
| 背景说明 |
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte potentiating factor, which belongs to the mesothelin family. Mesothelin/MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin/MSLN can interacts with MUC16. The membrane-anchored form of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
|
| Accession |
Q13421-1
|
实验结果图
1μg (R: reducing conditions, N: non-reducing conditions).