LE 300 is a potent and selective D1DR (dopamine D₁ receptor) antagonist with K_i values of 0.08-1.9 nM and 6-45 nM for D1DR and D2DR respectively. LE 300 also displays moderate affinity for the 5-HT_2A receptor (K_i = 20 nM).

A potent and selective D1DR receptor antagonist

≥99%

Store at room temperature

Solid

n²⁰_D 1.63 (Predicted)

Soluble in 1eq. HCl (50 mM), DMSO (100 mM), and ethanol (10 mM).

4350931