Recombinant human HLA-DOB protein
货号：
P03724
品牌：
Jinpan
产品简介
| 基因名 | HLA-DOB |
| 英文全称 | major histocompatibility complex, class II, DO beta |
| 别称 | DOB;HLA_DOB;major histocompatibility complex;class II;DO beta |
| 中文名称 | HLAⅡ类组织相容性抗原β |
| Uniprot | P13765 |
| GeneID | 3112 |
| 交叉反应(推测) | Human |
| 氨基酸大小 | 31kDa |
| 表达氨基酸 | 1-273aa |
| Background | HLA-DOB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane.It is located in intracellular vesicles.DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM.Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).The beta chain is approximately 26-28 kDa and its gene contains 6 exons.Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug 50ug 100ug 1mg |
