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监控人类细胞移植用途的抗体Engrafted Cell Markers
品牌	Code No.	产品名称	包装量	价格（元）	说明书	数量
Cellartis	Y40400	STEM101™	50 μg	￥2,251
Cellartis	Y40410	STEM121™	50 μg	￥2,281
Cellartis	Y40420	STEM123™	50 μg	￥2,246

监控人类细胞移植用途的抗体 (Antibodies for Detecting Human Cells Transplanted into Mice and Rats)

STEM101、STEM121、STEM123是三种小鼠来源的单克隆抗体，用于人类细胞向小鼠和大鼠移植实验中，监控细胞移植、转移、分化。   ■ 产品特点 · STEM101 reacts specifically with the nuclear human Ku80 protein; the antibody does not cross-react with mouse or rat Ku80 in brain tissue or cell extracts Note: STEM101 (Y40400) is not suitable for immunohistochemically staining on paraffin embedded tissue sections. We recommend using fresh frozen tissue with this antibody. · STEM121 reacts with a human cytoplasmic protein expressed in brain, liver, pancreas, and CNS cells the antibody does not cross-react with brain tissue or cell extracts from mouse, rat, or cynomologous monkey · STEM123 reacts specifically with human GFAP, a marker of astroglial cells; the antibody does not cross-react with brain tissue or cell extracts from mouse or rat   ■ 产品应用 · Localization, quantification, and/or characterization of engrafted cells of human origin by immunohistochemistry and immunofluorescence       ■ 产品详情请点击：

STEM101 detects nuclei of transplanted human neural stem cells in the olfactory bulb of a mouse brain.

STEM121 detects migration and differentiation of transplanted human neural stem cells in the hippocampus of a mouse brain.

STEM123 detects human GFAP+ astrocytes differentiated from human neural stem cells after transplantation into a mouse brain.

参考文献：

1. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074. 2. Guzman R, et al. (2007) Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. PNAS 104: 10211-10216. 3. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319. 4. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5: e12272. 5. Kelly S, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. PNAS (2004) 101:11839 11844. 6. Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074. 7. Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319. 8. Kallur T, et al. Human Fetal Cortical and Striatal Neural Stem Cells Generate Region-Specific Neurons In Vitro and Differentiate Extensively to Neurons After Intrastriatal Transplantation in Neonatal Rats. J Neurosci Res. (2006) 84:1630-1644. 9. Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5: e12272. 10. Tamaki SJ, et al. (2009) Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell 5:310-319. 11. Salazar DL, et al. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE 5:e12272. 12. Cummings BJ, et al. (2005) Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS 102: 14069-14074.

页面更新：2024-02-29 10:57:18