Gegentana, et al. J Ethnopharmacol. 2020 Aug 10;258:112886.
产品简介
MDL
MFCD00002398
EC
EINECS 200-618-2
别名
苄酸;安息香酸
英文名称
Benzoic acid
CAS
65-85-0
分子式
C6H5COOH
分子量
122.12
纯度
GC≥99%
单位
瓶
生物活性
Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.[1]
SMILES
O=C(O)C1=CC=CC=C1
靶点
Bacterial
数据来源文献
[1]. Nair B, et al. Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. Int J Toxicol. 2001;20 Suppl 3:23-50.
A positive drug (indomethacin, 20 mg/kg) and a non-positive drug (benzoic acid, 20 mg/kg) were mixed (1:1) and orally administered to the 6 different rats. The other experimental conditions and methods are the same as those discussed in 2.4.1.
来源文献:Gegentana, Xu F, Li FC, Zhang YF, Shen SJ, Yang P, Yang XX, Shang MY, Liu GX, Li YL, XuanWang, Cai SQ. Discovery of the active compounds of Smilacis Glabrae Rhizoma by utilizing the relationship between the individual differences in blood drug concentration and the pharmacological effect in rats. J Ethnopharmacol. 2020 Aug 10;258:112886. doi: 10.1016/j.jep.2020.112886. Epub 2020 Apr 21. PMID: 32325179.