牛CD分子抗体 Abd serotec公司

发表于2024年5月12日由上海金畔生物科技有限公司

牛CD标志物抗体

许多顶级刊物文章中经常引用的兽医免疫学试剂很多都来自AbD Serotec，AbD Serotec 可提供多种针对牛CD标志物的抗体。这些抗体主要是用来研究牛适应性和先天性免疫系统，可帮助阐释T细胞、B细胞、树突细胞和巨噬细胞的功能。同时，我们将继续开发基础免疫功能、诊断和疫苗开发试剂，并且保证所有的试剂都要通过验证合格才可出厂。

Cow CD Marker Antibodies

Specificity	Clone	Applications	Product Code	Format	T cell	B cell	Dendritic cell	NK cell	Monocyte/macrophage
CD1w2	CC13	F	MCA1646G	Purified			✓
CD1w2	CC20	C, F, IP	MCA2058G	Purified, RPE, S/N			✓
CD1w2	CC14	C, F, IP	MCA831G	Purified, Ascites			✓
CD1w3	CC43	F, IP	MCA1647G	Purified, S/N		✓	✓		✓
CD2	CC42	C, F, IP, P	MCA833G	Purified, Ascites, FITC	✓			✓
CD4	CC8	C, F, IP	MCA1653GA	Purified, Alexa, Fluor® 647, FITC, RPE	✓
CD4	CC30	C, F, IP, P	MCA834GA	Purified	✓
CD5	CC17	C, F, IP	MCA835G	Purified, Alexa, Fluor 647, FITC	✓	✓
CD6	CC38	C, F, IP	MCA836	Ascites	✓
CD8	CC63	C, F, IF, IP, P	MCA837GA	Purified, Alexa, Fluor 647, FITC, RPE		✓		✓
CD8beta	CC58	F, IP	MCA1654G	Purified, RPE		✓
CD11a	IL-A99	F, IP	MCA2429	Purified, FITC, RPE	✓	✓	✓	✓	✓
CD11b	CC126	C, F, IP	MCA1425GA	Purified, FITC				✓	✓
CD13	CC81	F	MCA2338	Purified, FITC			✓
CD14	CC-G33	F, IF	MCA2678GA	Purified, FITC					✓
CD21	CC21	C, F, IF, IP	MCA1424GA	Purified, FITC, RPE		✓
CD21	CC51	F	MCA5953GA	Purified, FITC, RPE		✓
CD25	IL-A111	C, F, IP	MCA2430GA	Purified, FITC, RPE	✓			✓
CD26	CC69	F, IP	MCA1652G	Purified, Alexa, Fluor 647, S/N		✓	✓	✓
CD28	CC219	F, FN	MCA5779	Purifi ed, FITC, EL, RPE	✓
CD28	CC220	F, FN	MCA5778	Purified, EL	✓
CD32	CCG36	C, F	MCA5918GA	Purified, FITC, RPE		✓	✓		✓

Cow CD Marker Antibodies

Specificity	Clone	Applications	Product Code	Format	T cell	B cell	Dendritic cell	NK cell	Monocyte/macrophage
CD32	CCG39	C, F	MCA5919GA	Purified, FITC		✓	✓		✓
CD40	IL-A156	F, FN	MCA2431GA	Purified, FITC, RPE		✓
CD41	IL-A164	C, F, IP	MCA2432	Purified, FITC, RPE
CD44	IL-A118	F	MCA2433	Purified, FITC, RPE	✓	✓			✓
CD45	CC1	C, F, IP	MCA832GA	Purified, FITC	✓	✓
CD45RB	CC76	C, F, IP	MCA1650G	Purified, FITC, S/N	✓
CD45RO	IL-A116	F, IP	MCA2434GA	Purified, RPE	✓				✓
CD62L	CC32	F	MCA1649G	Purified, FITC, S/N	✓	✓		✓	✓
CD63	CC25	F	MCA2042GA	Purified			✓		✓
CD80	IL-A159	F	MCA2436GA	Purified, FITC, RPE		✓	✓		✓
CD80	IL-A190	F	MCA2437GA	Purified, FITC, RPE		✓	✓		✓
CD172a	CC149	F	MCA2041GA	Purified, RPE-Cy5			✓		✓
CD205	CC98	C, F, IP	MCA1651GA	Purified, FITC			✓
CD205	IL-A114	C, F	MCA2450GA	Purified, FITC, RPE			✓
CD282	12542	F	HCA151	Purified, Alexa, Fluor 647, FITC			✓		✓
CD282	12538	F	HCA152	Purified, Alexa, Fluor 647, FITC			✓		✓
CD335	AKS1	F, FN, IF, WB	MCA2365GA	Purified, Alexa, Fluor 488, EL, RPE				✓

Applications: C = Immunohistology – Frozen, CT= Cytotoxic Assays, E = ELISA, F = Flow Cytometry, FN= Functional Assays,
IF= Immunofluorescence, IP = Immunoprecipitation, P = Immunohistology – Paraffin, WB = Western Blotting.

*信息来自内部实验室测试、同行评审刊物或研究人员的个人交流。

天然免疫学热点领域科研抗体(AbD Serotec®)—抗独特型(idiotype)抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—抗独特型(idiotype)抗体

关于抗独特型抗体
丹麦免疫学家Jerne 于1974 年提出了在独特型决定簇与抗独特型决定簇之间相互识别、相互作用基础上的“免疫网络学说”(immune network theory) 。该学说在承认细胞系选择学说的基础上, 认为免疫应答并非仅由某个单一克隆细胞的激活而实现。独特型决定簇具有自身免疫原性, 体内存在能识别自身独特型决定簇的淋巴细胞。机体接受外来抗原刺激时, 能识别外来抗原的淋巴细胞克隆首先被激活, 产生针对外来抗原的抗体(antibody ,Ab1 ) , 随后能识别某一个克隆独特型决定簇的第2 个克隆被激活, 产生抗独特型抗体(Ab2 ) , 依次类推还可以有第3 个(Ab3 ) ,第4 个(Ab4 ) ⋯⋯。这些克隆相互制约, 相互连锁, 形成一个闭合型、多层次级联网络。网络的主要作用是抑制抗体的产生, 因为只有抑制才能保持机体的免疫自稳状态, 使抗体维持在一定水平上。否则, 抗体无休止地产生, 反而会使机体患免疫病。免疫系统网络学说已经被实验所证明, 有力地促进和指导了基础免疫学的研究和发展。独特型(idiotype ,Id) 即位于抗体分子可变区的抗原决定簇, 是位于抗体可变区内高变区的遗传标志。本质上, Id 的差异是由抗体轻链可变区(VL ) 和抗体重链可变区(VH) 内高变区氨基酸序列不同所致。这种氨基酸序列的差异也是抗体特异性的分子基础, 不同特异性的抗体分子其独特型也不同。独特型由若干表位组成, 称为独特位(idiotope) , 它可刺激机体产生相应的抗体, 即抗独特型抗体(anti-idiotypic antibody , AId)。

应用
抗独特型抗体在抗体药物研发及监控过程的应用具有重要意义。当将人源抗体或人源化的抗体用于病人时，抗体药物会被病人血清中高浓度的结构相似的抗体所掩盖(hidden)。通常，抗体药物的浓度要比血清中抗体的浓度低百万倍，因此导致很难检测和定量抗体药物。给药后，要检测血药浓度或药代动力学参数，就需要高特异性、高灵敏度的试剂与抗体药物结合，而不与大量类似的免疫球蛋白相结合，抗独特型抗体即可满足与抗体药物的特异性结合，从而实现检测病人体内的药物水平。

检测方法
目前使用的技术主要有几下几种，其中方法a使用的较少，易产生假阳性。

AbD Serotec公司可提供针对以下几种常见的治疗性单抗的抗独特型抗体

Clone	Product Code	Antibody Specificity	Format	Affinity kD, nM
16748-hIgG1	HCA184	Bevacizumab	Human IgG1	2.0 nM*
17976	HCA182	Bevacizumab	Fab-V5Sx2¹	0.4 nM
17976-hIgG1	HCA185	Bevacizumab	Human IgG1	0.4 nM*
16712	HCA166	Trastuzumab	Fab-V5Sx2¹	0.4
16714	HCA167	Trastuzumab	Fab-V5Sx2¹	2.5
18018	HCA168	Trastuzumab	Fab-FH²	0.02
18141	HCA169	Trastuzumab	Fab-FH²	0.07
16712-hIgG1	HCA176	Trastuzumab	Human IgG	0.4*
18018-hIgG1	HCA177	Trastuzumab	Human IgG	0.02*
16728	HCA174	Alemtuzumab	Fab-V5Sx2¹	1.6
16942-hIgG1	HCA175	Alemtuzumab	Human IgG1	2.4*
16942-hIgG1	HCA175P	Alemtuzumab	HRP Conjugated	2.4*
19189	HCA198	Alemtuzumab	Fab-FH²	0.2
19189-hIgG1	HCA199	Alemtuzumab	Human IgG1	0.2
17837	HCA212	Infliximab	Fab-V5Sx2¹	0.9
17841-hIgG1	HCA213	Infliximab	Human IgG1	3.9*
19376	HCA214	Infliximab & Infliximab/TNF-α complex	Fab-FH²	0.7
19370-hIgG1	HCA215	Infliximab & Infliximab/TNF-α complex	Human IgG1	1.4*
19376-hIgG1	HCA216	Infliximab & Infliximab/TNF-α complex	Human IgG1	0.7*
18654	HCA202	Adalimumab	Fab-FH¹	0.16
18654-hIgG1	HCA203	Adalimumab	Human IgG1	0.16*
18655-hIgG1	HCA204	Adalimumab	Human IgG1	0.06*
18664-hIgG1	HCA205	Adalimumab	Human IgG1	10.5*
18754	HCA206	Adalimumab/TNF-α	Fab-FH¹	67
18754-hIG1	HCA207	Adalimumab/TNF-α	Human IgG1	67*
17829	HCA208	Ustekinumab	Fab-V5Sx2¹	2.8
18334	HCA209	Ustekinumab	Fab-FH²	0.4
17827-hIgG1	HCA210	Ustekinumab	Human IgG1	0.2*
17829-hIgG1	HCA211	Ustekinumab	Human IgG1	2.8*
18423	HCA186	Rituximab	Monovalent Fab-FH¹	0.13
18423-hIgG1	HCA201	Rituximab	Human IgG1	0.13*
MB2 A4	MCA2260	Rituximab	Rat IgG2a	Unknown
MB2 A4	MCA2260	Rituximab	HRP & FITC formats available	Unknown
2844	HCA062	Rituximab	Fab-dHLX-MH²	10.0*
2844	HCA062	Rituximab	HRP format available	10.0*
2842	HCA061	Rituximab	Fab-dHLX-MH²	4.9*
2842	HCA061	Rituximab	HRP format available	4.9*
19834	HCA220	Cetuximab	Fab-FH1	0.5
19830	HCA221	Cetuximab	hIgG1	1.7
19834	HCA222	Cetuximab	hIgG1	0.5
19815	HCA223	Cetuximab	hIgG1	10.5
19376	HCA228	Infliximab2	hIgG1	39

目前在研发中的，还有针对另外两个单抗药物的抗独特型抗体：Golimumab (SIMPONI®) 和Omalizumab (XOLAIR®)

简写说明: APC = Allophycocyanin, A405 = Alexa Fluor® 405, A488 = Alexa Fluor® 488, A647 = Alexa Fluor® 647, A700 = Alexa Fluor® 700, A750 = Alexa Fluor® 750, Az. Fr. = Azide Free,,Biot. = Biotin, LE = Low endotoxin, PB= Pacific BlueTM, Pur. = Purified, S/N=Supernatant
C = Immunohistology – Frozen, E = ELISA, F = Flow Cytometry, FN = Functional Assay, IF = Immunofluorescence, IP = Immunoprecipitation, P = Immunohistology – Paraffin,WB = Western Blotting.
* = Requires Special Conditions – see datasheet

天然免疫学热点领域科研抗体(AbD Serotec®)—报告蛋白抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—报告蛋白抗体

报告蛋白通过酶催化或荧光直读的方式来监测细胞转染、蛋白表达模式以及启动子功能。这些报告蛋白可以直接检测，或者像下图利用报告蛋白特异性抗体对报告蛋白进行western blot检测。

使用mouse anti-GST(MCA1352)和anti-mouse IgG-HRP(STAR13B )对GST-ubiquitin 进行Western blot检测

AbD Serotec公司最受欢迎的的报告蛋白抗体

产品名称	克隆号	形式	应用	产品编号
B- Galactosidase	4722 HuCAL	Purified	E	HCA033
	4723 HuCAL	Purified	E	HCA034
	4724 HuCAL	Purified	E	HCA035
Green Fluorescent Protein (GFP)	264-449-2	Purified	C, IB, IP	OBT1643
	338 HuCAL	Purified	E	HCA060
	N/K	Purified	C, E, P, WB	OBT1820
	Poly	Purified	E, IF	4745-1051
	Poly	Purified	E, IF, WB	AHP975
	Poly	Purified	E, IB	OBT1645
Glutathione-S- Transferase (GST)	2021 HuCAL	Purified	E, WB	HCA055
	2031 HuCAL	Purified, FITC, HRP	E, WB	HCA056
	3937 HuCAL	Purified	E, WB	HCA054
	Vpg66	S/N,Biotin	E, IF, WB	MCA1352
Luciferase	BGN/06/942	Purified	E	5709-4360
	BGN/06/944	Purified	E	5709-4380
	LUC-Y	Purified	C, E, F, WB	MCA2076

天然免疫学热点领域科研抗体(AbD Serotec®)—标签抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—标签抗体

表位标签(epitope tags)是小分子已知序列的的DNA，通过克隆与目的蛋白序列连接，附加了表位标签的蛋白质可以用针对该标签特异性的抗体来进行检测。表位标签的引入可以简化蛋白纯化的步骤，而且在无法获取目的蛋白特异性抗体的情况下，使用标签可以实现多种免疫检测。因此表位标签减少了蛋白特异性抗体生产的必要性，特别适用于无法获得相应种属抗体的情况。

AbD Serotec公司提供的最受欢迎的标签抗体

标签	克隆号	形式	应用	产品编号	其他形式
c-Myc	9E10	Purified	C, E, F, IF, P, WB	MCA2200	Alexa Fluor®488, Alexa Fluor®647, AP, Biotin, DyLight®549, FITC, HRP, RPE
c-Myc	JAC6	Purified	C, IF, IP, WB	MCA1929
c-Myc	3C7	Purified	IP, WB	OBT3187G
DYKDDDDK	Poly	Purified	E, WB	AHP1074GA	HRP
DYKDDDDK	Poly	Purified	E, IF	4497-1010
Hemagglutinin (HA)	Poly	Purified	E, P, WB	AHP1075GA
Histidine (6-His)	AD.1.10	Purified	C, E, IF, IP, WB	MCA1396	Alexa Fluor®488, Alexa Fluor®647,AP, Biotin, DyLight®549, DyLight® 800, FITC, HRP
Histidine (6-His)	Poly	Purified	E, IF, PP, WB	AHP1656	Biotin, FITC
S-Tag	SBSTAGa	Purified	E, F, PP	460001
S-Tag	SBSTAGa	HRP	E, PP	460005
S-Tag	SBSTAGa	Purified	E, F	MCA4668GA	FITC, HRP, RPE
S-Tag	SBSTAGb	Purified	E, F, PP	460101
S-Tag	SBSTAGb	Purified	E, F	MCA4669GA	Biotin, FITC, HRP, RPE
S-Tag	SBSTAGc	Purified	E, F, PP	460201
S-Tag	SBSTAGc	Purified	E, F, PP	MCA4670GA	FITC, HRP, RPE
S-Tag	Poly	Purified	E, F, PP	650001
STREP	Strep-tag II	Purified	E, WB	MCA2489	HRP
V5	SV5-Pk1	Purified	C, E, F, IF, IP, R, WB	MCA1360GA	Alexa Fluor®488, Alexa Fluor®647,AP, Biotin, DyLight® 405, DyLight®549, FITC, HRP
V5	SV5-Pk 2	Purified	E, IP, WB	MCA2892GA
V5	SV5-Pk 3	Purified	E, IP, WB	MCA2893GA
V5	SV5-Pk4	Purified	E, IF, IP, WB	MCA2894GA	DyLight®549, DyLight®649, FITC
V5	SV5-Pk5	Purified	E, IF, IP, WB	MCA2895GA	FITC, DyLight®549, DyLight®649
VSV-G	Poly	Purified	E, IF, WB	AHP1228	Biotin

天然免疫学热点领域科研抗体(AbD Serotec®)—模式识别受体抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—模式识别受体抗体

天然免疫系统发挥防御作用的关键是对病原体的识别,这一识别主要由模式识别受体(pattern recognition receptors,PRR)完成。模式识别受体包含存在于巨噬细胞和树突状细胞表面的膜连受体及胞浆内和分泌的模式识别受体。

AbD Serotec公司提供的最受欢迎的模式识别受体抗体

人模式识别受体抗体
产品名称	克隆号	产品编号	形式
CD205	MG38	MCA2258	Pur., FITC, LE, RPE
CD206	15-2	MCA2155	Pur.
CD206	7-450	MCA2519	Pur.
CD209	MR-1	MCA2318	Pur., A488, A647, Biot., FITC, LE, RPE
DAI	Poly	AHP1780	Pur.
Dectin-1	BD6	MCA4662	Pur., A488, A647, FITC, RPE
Dectin-1	GE2	MCA4661	Pur., A488, A647, FITC, LE, RPE
IPAF	Poly	AHP1779	Pur.
LGP2	Poly	AHP1777	Pur.
LGP2	Poly	AHP1778	Pur.
LOX-1	Poly	AHP952	Pur.
LOX-1	Poly	AHP1601	Serum
LOX-1	Poly	AHP1602	Serum
LOX-1	LOX19-22	MCA2765	Pur.
LOX-1	LOX20-7	MCA2766	Pur.
MBP-C	SM2 (BGN/08/082)	5937-1015	Pur.
MBP-C	SM4 (BGN/08/084)	5937-1025	Pur.
MD-2	Poly	AHP1717	Pur.
Mucin 2	996/1	MCA1743	Pur., FITC
NALP1	Poly	AHP1772	Pur.
NALP3	Poly	AHP1774	Pur.
NAIP	Poly	AHP1775	Pur.
NOD2	Poly	AHP1015	Pur.
PTX3	2B10	MCA4129Z	Az. Fr.
RIG-I	Poly	AHP1776	Pur.
小鼠模式识别受体抗体
TREM-1	TREM-37	MCA4697T	Pur.
TREM-1	TREM-26	MCA4698T	Pur., Biot., RPE
CD205	NLDC-145	MCA949	S/N, A488, A647, A700, FITC
CD206	MR5D3	MCA2235	Pur., A488, A647, Biot., FITC, LE, RPE
CD301	ER-MP23	MCA2392	Pur., A488, A647, Biot., LE
Dectin-1	2A11	MCA2289	Pur., A647, Biot., FITC, LE, RPE
Dectin-2	D2.11E4	MCA2415	Pur., A488, A647, Biot., FITC, LE, RPE
RIG-I	SS1A	MCA4695T	Pur.
SIGN-R1	ER-TR9	MCA2394	Pur., A488, A647, Biot., LE
TREM-1	L5- B8.2A12.3A12	MCA2578	Pur., A488, A647, FITC
TREM-2	78.18	MCA4772	Pur., FITC, LE, RPE

天然免疫学热点领域科研抗体(AbD Serotec®)—补体系统相关抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—补体系统相关抗体

补体系统（Complement System）由近35种蛋白组成，经连锁相互反应产生不同的生物学效应，广泛参与机体微生物防御反应以及免疫调节，可中和和破坏外源病原体和凋亡细胞。AbD Serotec公司提供丰富的抗体可用于研究补体激活的3个途径，包括相关受体和调节蛋白。

AbD Serotec公司精选补体系统相关抗体

产品名称	克隆号	产品编号	形式
C1q	Polyclonal	AHP033	Pur., FITC
C1q	Polyclonal	2221-5004	HRP
C1q	3R9/2	MCA2603	Pur.
C3a	10-21	MCA2604	Pur.
C3a receptor	hC3aRZ1	MCA2455	Pur., A488, A647, RPE
C3b	H11	0200-0614	Pur.
C3c	10-02A	MCA2605	Pur.
C3d	053A-1149.3.1.4 (1003)	MCA2606	Pur.
C3d	053A-514.3.1.4	MCA2648	Pur.
C4BP	10-07	MCA2609	Pur.
C4c	10-12	MCA2608	Pur.
C4d	10-11	2222-8004	Pur.
C4d	TDM16	MCA5766GA	Pur.
C4d	TDM37	MCA5767GA	Pur.
C4d	Polyclonal	0300-0230	Pur.
C5	10-04	MCA2610	Pur.
C6	056B-214.2.4.2	MCA2666	Pur.
C7	030-113.7.5.4	MCA2644	Pur.
C8	056B-373	MCA2645	Pur.
C9	002-94.8.8	MCA2646	Pur.
CD11c	BU15	MCA2087	Pur., A488, A647, FITC, RPE
CD18	Bu86	MCA2510	Pur., FITC
CD18	YFC118.3	MCA503	Pur., A647, Biot., FITC, RPE, LE
CD18	MEM-148	MCA2086	Pur., Az. Fr., Biot., FITC, RPE
CD21	LB21	MCA1195	Pur., FITC, RPE
CD21	2G9	MCA1808	S/N
CD21	Bu32	MCA2498	Pur., FITC
CD21	Bu33	MCA2499	Pur.
CD35	E11	MCA554	Pur., Az. Fr., FITC, RPE
CD46	MEM-258	MCA2113	Pur., A647, FITC, RPE
CD55	67	MCA1614	Pur., RPE
CD55	1G3	MCA4011Z	Az. Fr.
CD55	BRIC216	MCA914	Pur.
CD59	MEM-43	MCA1054	Pur., A647, Az. Fr., Biot., FITC, RPE, A488
CD59	YTH53.1	MCA715G	Pur., FITC, RPE
Clusterin	3R3/2	MCA2612	Pur.
Complement factor B	10-09	MCA2613	Pur.
Complement factor B	014III-33.2.4.3	MCA2647	Pur.
Complement factor Bb	032B-22.1.X	MCA2650	Pur.
Complement factor H	10-10	MCA2614	Pur.
Complement factor I	3R/8	MCA2615	Pur.
Complement factor P	10-18	MCA2617	Pur.
Complement factor P	10-24	MCA2618	Pur.
CRIT	4644	HCA031	Pur.
iC3b	013III-1.16	MCA2607	Pur.
Mannan binding protein	SM2 (BGN/08/082)	5937-1015	Pur.
Mannan binding protein	SM4 (BGN/08/084)	5937-1025	Pur.
SC5b-9	3R2/0	MCA2611	Pur.

天然免疫学热点领域科研抗体(AbD Serotec®)—经典大鼠CD分子抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—经典大鼠CD分子抗体

● 丰富的大鼠抗体产品
● 品质保证
● 专业的技术支持
● 批量生产能力
● 抗体定制服务
● 生产符合国际ISO9001标准

CD68，mouse anti rat clone ED1(MCA341) CD163，mouse anti rat clone ED2(MCA342)

是最著名的大鼠巨噬细胞标志物抗体 识别腹膜巨噬细胞、脾巨噬细胞以及其他多

大鼠肝脏（经诱导的肝细胞损伤）的免疫组化 种组织中巨噬细胞表面糖蛋白CD163。经丙
染色结果，使用抗体为mouse anti rat CD68 酮固定的大鼠脾脏冰冻切片组化染色结果，使用
(MCA341GA）抗体为mouse anti rat CD163(MCA342GA)

AbD Serotec公司提供的最受欢迎的抗大鼠抗体

产品名称	克隆号	产品编号	形式
C3	ED11	MCA733R	Pur.
CD115	604B5 2E11	MCA1898	Pur., Az. Fr., RPE
CD11b	OX-42	MCA275	Pur., A488, A647, A700, Biot., FITC, LE, PB, RPE, RPE-A647
CD11b	ED7	MCA618R	Pur.
CD11b	ED8	MCA619	Pur., FITC, RPE
CD11c	8A2	MCA1441	Pur., A647, FITC
CD161	10/78	MCA1427	Pur., Az. Fr., A488, A647, Biot., FITC, RPE
CD163	ED2	MCA342	Pur., A647, Biot., FITC, LE, RPE
CD169	ED3	MCA343	Pur.
CD172a	OX41	MCA274	Pur., Az. Fr., Biot, FITC, RPE
CD172a	ED9	MCA620	Pur., FITC, RPE
CD18	WT.3	MCA775	Pur., Az. Fr., FITC, RPE
CD1d	WTH1	MCA5799	Pur., Biot., FITC
CD1d	WTH2	MCA5800	Pur., Biot., FITC
CD2	OX-34	MCA154	Pur., A488, A647, Az. Fr., Biot., FITC, RPE
CD200	OX-2	MCA44	Pur., Az. Fr., FITC, RPE
CD200R1	OX-102	MCA1959	Pur., Biot., FITC, LE, RPE
CD25	OX-39	MCA273	Pur., A488, A647, Biot., FITC, LE, RPE
CD28	JJ319	MCA1331	Pur., A488, A647, FITC, LE, RPE
CD3	1F4	MCA772	Pur., A647, A700, Az. Fr., Biot., FITC, PB
CD31	TLD-3A12	MCA1334	Pur., A488, A647, Biot., FITC, LE, RPE
CD4	OX-35	MCA153	Pur., A647, Az.Fr., FITC, RPE
CD4	W3/25	MCA55	Pur., A488, A647, A700, APC, Az.Fr., Biot., FITC, PB, RPE, RPE- A647, RPE-A750
CD43	W3/13	MCA54	Pur., Biot., FITC, RPE
CD44	OX-50	MCA643	Pur., Az.Fr., FITC, RPE, S/N
CD45	OX-1	MCA43	Pur., A488, A647, A700, Biot., FITC, RPE, RPE-A647, RPE-A750
CD45	OX-29	MCA589	Pur., S/N
CD45R	HIS24 (6B6)	MCA1326	S/N
CD45RA	OX-33	MCA340	Pur., A488, FITC, RPE, RPE-A647
CD5	OX-19	MCA52	Pur., A488, A647, Biot., FITC, RPE
CD54	1A29	MCA773	Pur., A488, A647, Biot., FITC, LE, RPE
CD63	AD1	MCA4754	Pur., A488, A647, FITC, RPE
CD68	ED1	MCA341	Pur., A488, A647, A700, Biot., FITC, RPE
CD71	OX-26	MCA155	Pur., Biot., FITC, LE, RPE
CD8 ALPHA	OX-8	MCA48	Pur., A488, A647, Az.Fr., Biot., FITC, RPE, RPE-A647
CD80	3H5	MCA2873	Pur., A488, A647, FITC, LE
CD86	24F	MCA2874	Pur., A488, A647, FITC, LE, RPE
CD90	T11D7e	MCA04	Pur.
CD90	OX-7	MCA47	Pur., A488, A647, Biot., FITC, LE, RPE, RPE-A647
CGRP	Polyclonal	1720-9007	Pur.
Collagen III	Polyclonal	2150-1950	Pur.
ED5 antigen	ED5	MCA530R	Pur.
FOXO1	Polyclonal	AHP2244	Pur.
FOXO3A	Polyclonal	AHP2245	Pur.
IFN GAMMA	DB-1	MCA1301	Pur., Az.Fr., FITC
IgE	MARE-1	MCA193	Pur, FITC, Biot., HRP
IgG	Polyclonal	AAR10	Biot, FITC, HRP
IgG1	8941	HCA118	Pur., HRP
IgG1	8938	HCA119	Pur., HRP
IgG2a	9345	HCA120	Pur., HRP
IgG2b	9204	HCA129	Pur., HRP
IgG2C	9337	HCA142	Pur., FITC, HRP
IL-1 BETA	Polyclonal	AAR15	Pur., Biot.
IL-10	Polyclonal	AAR29	Pur., Biot.
MCP-1	Polyclonal	AAR31	Pur., Biot.
MHC CLASS I RT1A	OX-18	MCA51	Pur., Biot., FITC, RPE
MHC CLASS I RT1Ac	OX-27	MCA156	Pur., FITC, RPE
MHC CLASS II RT1B	OX-6	MCA46	Pur., A488, A647, Biot., FITC, RPE
MHC CLASS II RT1Bu/l	OX-3	MCA45	Pur., Biot., FITC, RPE
OX-62	OX-62	MCA1029	Pur., Biot., RPE
RECA-1	HIS52	MCA970	Pur.
RETICULUM CELLS	ED10	MCA732	Pur
STEM CELL FACTOR	Polyclonal	AAR44	Pur., Biot.
TNF ALPHA	Polyclonal	AAR33	Pur., Biot

大鼠荧光双染试剂盒

产品名称	克隆号	产品编号	形式
CD4/CD25	W3/25/OX-39	DC040	FITC/RPE
CD3/CD4	IF4/W3-25	DC041	FITC/RPE
CD3/CD8	IF4/OX-8	DC042	FITC/RPE
CD3/CD45RA	IF4/OX-33	DC044	FITC/RPE
RAT MONOCLONAL ISOTYPING KIT		RMT1	KIT

天然免疫学热点领域科研抗体(AbD Serotec®)—自然杀伤细胞标志物抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—自然杀伤细胞标志物抗体

自然杀伤细胞(natural killer cell，NK)是机体重要的免疫细胞，不仅与抗肿瘤、抗病毒感染和免疫调节有关，而且在某些情况下参与超敏反应和自身免疫性疾病的发生。
天然免疫学热点领域科研抗体(AbD Serotec®)---自然杀伤细胞标志物抗体

人流式抗体试剂盒4C007可用于一步法鉴定和计数T细胞，B细胞和NK细胞。CD16/CD56是抗人CD16（克隆号LNK16）和抗人CD56（克隆号MEM-188）的混合抗体。左图为使用流式抗体试剂盒4C007对人淋巴细胞流式染色结果。CD3^–(CD16/CD56)⁺为NK细胞。

人CD16又称FcγRIIIA，IgG Fc段低亲和力受体。不同人NK细胞亚群CD16表达水平不同，而且抗体依赖性细胞毒作用（antibody-dependent cellular cytotoxicity）也有差异。左图为使用mouse anti human CD16(MCA1193)对人外周血单核细胞流式染色结果。

AbD Serotec公司提供的最受欢迎的NK细胞抗体

人NK细胞抗体
产品名称		克隆号	产品编号	形式
CD3/CD16/CD56/CD45/CD19		UCHT1 / LNK16 / MEM- 188 / F10-89-4 / LT19	4C007	FITC, RPE, PERCP, APC
CD2		LT2	MCA1194	Pur., A647, Biot., FITC, LE, RPE
CD11b		ICRF44	MCA551	Pur., A647, A700, Az.Fr., Biot., FITC, RPE, RPE-A647
CD11c		Polyclonal	AHP1226	Pur.
CD16		KD	MCA5665	Pur., FITC
CD16		LNK16	MCA1193	Pur., A647, Biot., FITC, LE
CD16/CD56		LNK16/MEM-188	MCA2074	FITC
CD27		LT27	MCA755	Pur., A647, Az.Fr., FITC, RPE
CD56		123C3	MCA2693	Pur., A488, A647, A700, FITC
CD56		C5.9	MCA1437	RPE
CD56		ERIC-1	MCA591	Pur., Az.Fr.
CD56		MEM-188	MCA2046	Pur., A647, Biot., FITC
CD62L		FMC46	MCA1076	Pur., FITC, RPE
CD66acd		YTH71.3	MCA1147	Pur.
CD81		1D6	MCA1847	Pur., FITC, LE
CD85j		4F9	MCA2515	Pur., A488, A647, FITC, RPE
CD94		DX22	MCA2254	Pur., Az.Fr., Biot., FITC, RPE
CD94		HP-3B1	MCA1537	Pur.
CD95		LOB 3/11	MCA1540	Pur., Az.Fr.
CD95		LOB 3/17	MCA1539	Pur., A647, FITC, RPE
CD95			PHP192	Rec. Protein
CD96		NK92.39	MCA4643	Pur., A488, A647, FITC, LE, RPE
CD158b		190IIC311	MCA2340	Pur., A488, RPE
CD158b		GL183	MCA1584	Pur.
CD161 (KLRB1)		B199.2	MCA1855	Pur., FITC, RPE
CD244		2B4.69	MCA2421	Pur., A488, Biot., LE, RPE
CD300a		P192	MCA5747	Pur., FITC, RPE
CD314		1D11	MCA2405	Pur., A488, A647, FITC, LE, RPE
CD335		N1d9	MCA2339	Pur.
CD335		9E2	MCA4646	Pur., A488, A647, FITC, LE, RPE
CD336		3.43	MCA4665	Pur., A488, A647
GRANZYME A		GA6	MCA2117	Pur.
GRANZYME B		GB11	MCA2120	Pur.
GRANZYME B		GB7	MCA2118	Pur.
IFN Gamma		B27	MCA1554	Pur., APC, Az.Fr., Biot., FITC, RPE
IFN Gamma		D9D10	MCA1581	Pur., FITC, RPE
SIGLEC-7		S7.7	MCA5782	Pur., FITC, LE
SIGLEC-9		K8	MCA5890	Pur., FITC
SIGLEC-10		5G6	MCA5783	Pur., FITC RPE
TNF ALPHA		Polyclonal	AHP1212	Pur., Biot.
TGF beta		TB21	MCA797	Pur.
小鼠NK细胞抗体
CD2	AT37		MCA1261	Az. Fr., FITC, RPE, S/N
CD11b	5C6		MCA711	Pur., FITC, LE, RPE
CD11b	M1/70.15		MCA74	Pur., A488, A647, A700, Biot., FITC, LE, RPE, RPE-A647, RPE-A750, RPE-CY5
CD11c	N418		MCA1369	Pur., A488, A647, Biot., FITC, RPE, RPE-A647, RPE-A750
CD27	LG.3A10		MCA4701	Pur., Biot., FITC, RPE
CD45	YW62.3		MCA1031	Pur., A488, A647, A700, Biot., FITC, LE, RPE
CD45R	RA3-6B2		MCA1258	Pur., A488, A647, A700, FITC, RPE, RPE-A647, RPE-A750, RPE-CY5, RPE-CY7
CD49b	DX5		MCA2125	Pur., Biot., FITC
CD62L	MEL-14		MCA1259	Pur., Az.Fr., RPE
CD94	18d3		MCA2288	Pur., A488, A647, Biot., FITC, RPE
CD127	SB/199		MCA2306	Pur., A488, A647, FITC
CD161b/c (NK1.1)	PK136		MCA1266	Pur., Az.Fr., Biot., RPE
CD335	29A1.4		MCA5938	Pur., Biotin, FITC, LE, RPE, RPE-CY7
CLEC-2	17D9		MCA5700	Pur., FITC, RPE
IFN Gamma	XMG1.2		MCA1548	Pur., Biot., FITC, LE, RPE
NKG2A/C/E	20d5		MCA2287	Pur., A488, A647, Biot., FITC, LE, RPE

天然免疫学热点领域科研抗体(AbD Serotec®)—树突状细胞标志物抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—树突状细胞标志物抗体

树突状细胞（Dendritic cells, DC）是机体功能最强的专职抗原递呈细胞(Antigen presenting cells, APC)，它能高效地摄取、加工处理和递呈抗原，在天然免疫和获得性免疫抗中发挥着重要的作用。

AbD Serotec公司精选的树突状细胞标志物抗体

人树突状细胞标志物抗体
产品名称	克隆号	产品编号	形式
CD1a	NA1/34-HLK	MCA80	Pur., A488, A647, Biot., FITC, RPE
CD1a	O10	MCA1657	Ready To Use
CD13	WM15	MCA1270	Pur., A488, A647, A700, APC, FITC, LE, RPE
CD40	LOB7/6	MCA1590	Pur., A488, A647, Biot., FITC, LE, RPE
CD43	DFT-1	MCA555	Pur., A647, Az. Fr., Biot., FITC, RPE
CD70	Bu69	MCA1765G	Pur.
CD80	MEM-233	MCA2071	Pur., A647, Az. Fr., Biot., FITC, RPE
CD83	HB15e	MCA1582	Pur., A488, A647, Biot., FITC, RPE, RPE-CY5
CD86	BU63	MCA1118	Pur., FITC, LE, RPE, RPE-CY5
CD91	A2Mr alpha-2	MCA1965	Pur., Az. Fr., Biot., FITC, RPE
CD103	LF61	MCA1416	Pur., FITC, LE, RPE, RPE-CY5
CD107b	Poly	AHP163	Pur.
CD123	6H6	MCA1263T	Pur., Az. Fr.
CD135	BV10A4H2	MCA1843	Biot.
CD141	QBEND/40	MCA641	S/N
CD184	Poly	AHP443	Pur.
CD196	4C6	MCA4623GA	Pur.
CD205	MG38	MCA2258	Pur., FITC, LE, RPE
CD206	15-2	MCA2155	Pur.
CD209	MR-1	MCA2318	Pur., A488, A647, Biot., FITC, LE, RPE
CD273	MIH14	MCA2630	Pur., A488, A647, FITC, RPE
CD274	MIH2	MCA2627	Pur., A488, A647, FITC, RPE
CD300a	MEM-260	MCA2704GA	Pur.
CD314	1D11	MCA2405	Pur., A488, A647, FITC, LE, RPE
Dectin-1	GE2	MCA4661	Pur., A488, A647, FITC, LE, RPE
Dectin-1	BD6	MCA4662	Pur., A488, A647, FITC, RPE
GITRL	Poly	AHP1865	Pur., Biot.
TSLP Receptor	Poly	AHP1431	Pur.
TSLP Receptor	4A11	MCA3918Z	Az. Fr.
小鼠树突状细胞标志物抗体
CD13	R3-63	MCA2183	Pur., A488, A647, Biot., FITC, LE, RPE
CD13	ER-BMDM1	MCA2395	Pur., A488
CD40	3/23	MCA1143	Pur., A488, A647, A700, Biot., FITC, LE,RPE, RPE- A647
CD43	1B11	MCA4702GA	Pur.
CD70	FR70	MCA2302	Pur., A488, A647, Biot., FITC
CD80	RM80	MCA2462	Pur., A488, A647, FITC, LE, RPE
CD83	3D11	MCA2747	Pur., A488, A647, FITC, RPE
CD86	RMMP-2	MCA1587	Pur., FITC
CD86	PO3	MCA2463	Pur., A488, A647, FITC, LE, RPE
CD103	2E7	MCA4705GA	Pur.
CD107b	M3/84	MCA2293	Pur., A488, A647, Biot., FITC, RPE
CD123	5B11	MCA2353	Pur., A488, A647
CD184	Poly	AAM67	Pur.
CD197	4B12	MCA2367	Pur., A488, A647, Biot., FITC, RPE
CD205	NLDC-145	MCA949	A488, A647, A700, FITC, S/N
CD206	MR5D3	MCA2235	Pur., A488, A647, Biot., FITC, LE, RPE
CD252	OX-89	MCA1881	Pur., Az. Fr.
CD273	TY25	MCA2465	Pur., A488, A647, FITC, LE, PB, RPE
CD274	MIH6	MCA2626	Pur., A488, A647, FITC, LE
Dectin-1	2A11	MCA2289	Pur., A647, Biot., FITC, LE, RPE
Dectin-2	D2.11E4	MCA2415	Pur., A488, A647, Biot., FITC, LE, RPE
Dendritic / interdigitating cells	MIDC-8	MCA948	S/N
GITRL	YGL386	MCA2417	Pur., A647, LE
大鼠树突状细胞标志物抗体
CD43	W3/13	MCA54	Pur., Biot., FITC, RPE
CD80	3H5	MCA2873	Pur., A488, A647, FITC, LE
CD86	OX-48	MCA2121	Pur., Biot., FITC, RPE
CD86	24F	MCA2874	Pur., A488, A647, FITC, LE, RPE
CD163	ED2	MCA342	Pur., A647, Biot., FITC, LE, RPE
CD200	OX-2	MCA44	Pur., Az. Fr., FITC, RPE
CD200R1	OX-102	MCA1959	Pur., Biot., FITC, LE, RPE

天然免疫学热点领域科研抗体(AbD Serotec®)—巨噬细胞标志物抗体

发表于2024年5月12日由上海金畔生物科技有限公司

天然免疫学热点领域科研抗体(AbD Serotec®)—巨噬细胞标志物抗体

AbD Serotec公司是全球领先的巨噬细胞标志物抗体供应商，其生产的MCA497, Rat Anti Mouse F4/80 Clone CI:A3-1是著名的成熟小鼠巨噬细胞表面特异性标志物抗体，有将近400篇的文献引用，提供多达30种的包装形式，可用于FC、WB，IF、IHC等7种应用。AbD Serotec享有该克隆的专利，是该抗体唯一的商业化生产商。
MCA1957识别小鼠细胞表面macrosialin，为人CD68的同源物，是专门表达于组织巨噬细胞的一种重度糖基化的跨膜糖蛋白。

小鼠淋巴结的免疫荧光染色；巨噬细胞用anti 小鼠脾脏冰冻切片的免疫组化染色；红髓中的
F4/80(MCA497PE)染成红色，B细胞用anti C- 巨噬细胞用anti CD68(MCA1957)染色
D79b(MCA1821A488)染成绿色，细胞核用D-
API复染，呈蓝色

AbD Serotec公司提供的最受欢迎的巨噬细胞标志物抗体

人巨噬细胞标志物抗体
产品名称	克隆号		产品编号	形式
CD11b	ICRF44		MCA551	Pur., A647, A700, Az. Fr., Biot., FITC, RPE, RPE-A647
CD14	UCHM1		MCA596	Pur., A647, APC, Az. Fr., Biot., FITC, RPE
CD14	TUK4		MCA1568	Pur., A647, A700, Biot., FITC, LE, PB, RPE, RPE-A647, RPE-A750
CD14	MEM-18		MCA2185	Pur., FITC, RPE
CD14	61D3		MCA2804	RPE-Cy5, RPE-Cy5.5
CD163	EDHu-1		MCA1853	Pur., FITC
CD169	7-239		MCA2517	Pur., A488, A647, FITC, LE, RPE
CD200R	OX108		MCA2282	Pur., A488, A647, Biot., FITC, RPE
CD204	Poly		AHP563	Serum
CD206	15-2		MCA2155	Pur.
CD209	MR-1		MCA2318	Pur., A488, A647, Biot., FITC, LE, RPE
CD31	WM59		MCA1738	Pur., A647, Biot., FITC, RPE
CD36	SMØ		MCA722	Pur., A647, Az. Fr., FITC
CD68	514H12		MCA1815	S/N
CD68	KiM7		MCA2375F	FITC
Dectin-1	BD6		MCA4662	Pur., A488, A647, FITC, RPE
Dectin-1	GE2		MCA4661	Pur., A488, A647, FITC, LE, RPE
Macrophage	MAC387		MCA874	Pur., A488, FITC, LE, RPE
小鼠巨噬细胞标志物抗体
CD11b		M1/70.15	MCA74	Pur., A488, A647, A700, Biot., FITC, LE, RPE, RPE- A647, RPE-A750, RPE-Cy5
CD11b		5C6	MCA711	Pur., FITC, LE, RPE
CD115		604B5	2E11	MCA1898 Pur., Az. Fr., RPE
CD169		MOMA-1	MCA947	Pur., S/N, A647, FITC
CD169		3D6.112	MCA884	Pur., FITC, LE
CD200R		OX-110	MCA2281	Pur., A488, A647, Biot., FITC, LE, RPE
CD204		2F8	MCA1322	Pur., A488, A647, Biot., FITC, LE, RPE
CD206		MR5D3	MCA2235	Pur., A488, A647, Biot., FITC, LE, RPE
CD31		ER-MP12	MCA2388	Pur., A488, A647, Biot., RPE, RPE-A647
CD36		MF3	MCA2748	Pur., A488, A647, FITC, LE, RPE
CD68		FA-11	MCA1957	Pur., A488, A647, A700, Az. Fr., Biot., FITC, RPE
Dectin-1		2A11	MCA2289	Pur., A647, Biot., FITC, LE, RPE
Dectin-2		D2.11E4	MCA2415	Pur., A488, A647, Biot., FITC, LE, RPE
F4/80		CI:A3-1	MCA497	Pur., A488, A647, A700, APC, Biot., FITC, LE, PB, RPE, RPE-A647, RPE-A750, S/N
Ly-6B.2		7/4	MCA771	Pur., A647, A700, Biot., FITC, LE, RPE
Ly-6C		ER-MP20	MCA2389	Pur., A488, A647, Biot., RPE
MARCO		ED31	MCA1849	Pur., FITC, RPE
TREM-1		L5-B8.2A12.3A12	MCA2578	Pur., A488, A647, FITC, LE, RPE
TREM-2		78.18	MCA4772	Pur., FITC, LE
大鼠巨噬细胞标志物抗体
CD11b		OX-42	MCA275	Pur., A488, A647, A700, Biot., FITC, LE, PB, RPE, RPE- A647
CD11b		ED7	MCA618R	Pur.
CD11b		ED8	MCA619	Pur., FITC, RPE
CD115		604B52E11	MCA1898	Pur., Az. Fr., RPE
CD163		ED2	MCA342	Pur., A647, Biot., FITC, LE, RPE
CD169		ED3	MCA343	Pur.
CD172a		OX41	MCA274	Pur., Az. Fr., Biot, FITC, RPE
CD172a		ED9	MCA620	Pur., FITC, RPE
CD200R1		OX-102	MCA1959	Pur., Biot., FITC, LE, RPE
CD31		TLD-3A12	MCA1334	Pur., A488, A647, Biot., FITC, LE, RPE
CD68		ED1	MCA341	Pur., A488, A647, A700, Biot., FITC, RPE

荧光多色染色试剂

产品名称	克隆号	产品编号	形式
Human CD45/CD14	F10-89-4/UCHM1	DC008	FITC/RPE
Mouse IgG2a/IgG2a	Negative Control	DC013	FITC/RPE
Mouse Ly6C/CD31	ERMP20/ERMP12	DC053	A488/RPE
Mouse Ly6C/CD31	ERMP20/ERMP12	DC054	A488/RPE-A647
Mouse CD11b/CD115	M1/70.15 / 604B5 2E11	DC055	A488/RPE
Mouse Ly6C/CD115/CD11b	ERMP20/604B52E11/M1/70.15	TC015	A488/RPE/RPE-A647
Mouse Ly6C/CD115/CD31	ERMP20/604B52E11/ERMP12	TC016	A488/RPE/RPE-A647
Mouse Ly6C/CD115/CD31	ERMP20/604B52E11/ERMP12	TC017	A488/RPE/A647
Mouse Ly6C/CD115/CD11b/CD31	ERMP20/604B52E11/M1/70.15/ERMP12	QC001	A488/RPE/RPE-A647/A647

AbD Serotec公司 F4/80 产品参考文献
1. Austyn, J.M. and Gordon, S. (1981) F4/80 , a monoclonal antibody directed specifically against the mouse macrophage.Eur. J. Immunol. 11: 805-815.
2. Hume, D.A., Perry, V.H., and Gordon, S. (1984) The Mononuclear Phagocyte System of the Mouse defined by Immunohistochemical Localisation of Antigen F4/80: Macrophages Associated with Epithelia.The Anatomical Record 210: 503-512.
3. Lee, S.H. et al. (1985) Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80.J. Exp. Med. 161: 475-489.
4. Gordon, S. et al. (1992) Antigen markers of macrophage differentiation in murine tissues.
Curr. Top. Micro. Immunol. 181: 1-37.
5. Uaesoontrachoon, K. et al. (2013) Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury.Dis Model Mech. 6: 197-205.
6. Lin, H. H.et al. (2005) The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance.J. Exp. Med. 201: 1615–1625.
7. Chan, R.J. et al. (2005) Human somatic PTPN11 mutations induce hematopoietic cell hypersensitivity to granulocyte-macrophage colony stimulating factor.Blood. 105: 3737-3742.
8. Pizza, F.X. et al. (2005) Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice.J. Physiol. 562:899-913.
9. Tarallo, V. et al. (2011) The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.J Biol Chem. 286: 19641-51.
10. Rivollier, A. et al. (2012) Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.
J Exp Med. 209: 139-55.
11. Hemmi, H. et al. (2009) A new triggering receptor expressed on myeloid cells (Trem) family member,Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linkedmarker for subsets of mouse macrophages and dendritic cells.J Immunol. 182:1278-86.
12. Seitz, O. et al. (2010) Wound Healing in Mice with High-Fat Diet- or ob Gene-Induced Diabetes-Obesity Syndromes: A Comparative Study.Exp Diabetes Res. 2010: 476969.
13. Miao, E.A. et al. (2011) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.Nat Immunol. 11: 1136-42.
14. Wang, X. et al. (2011) Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance.Endocrinology. 152: 836-46.
15. Cunningham, O. et al. (2009) Microglia and the urokinase plasminogen activator receptor/uPA system ininnate brain inflammation.Glia. 57: 1802-14.
16. Gornicka, A. et al. (2012) Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation.Am J Physiol Endocrinol Metab. 303: E597-606.
17. Akbarshahi, H. et al. (2012) Enrichment of Murine CD68(+)CCR2(+) and CD68(+)CD206(+) Lung Macrophages in Acute Pancreatitis-Associated Acute Lung Injury.PLoS One. 7: e42654.
18. Banda, N.K. et al. (1012) Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.J Immunol. 188: 1469-78.
19. Bonde, A.K. et al. (2012) Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors.BMC Cancer. 12: 35.
20. Choi, K.M. et al. (2010) CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice.Gastroenterology. 138: 2399-409,
21. Tamaki, S. et al. (2013) Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.PLoS One. 8: e68893.
22. Kihira, Y. et al. (2014) Deletion of hypoxia-inducible factor-1a in adipocytes enhances glucagon-like Peptide-1 secretion and reduces adipose tissue inflammation.PLoS One. 9(4):e93856.

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天然免疫学热点领域科研抗体(AbD Serotec®)—树突状细胞标志物抗体

天然免疫学热点领域科研抗体(AbD Serotec®)—巨噬细胞标志物抗体

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