5,7-Dihydroxy-3′,4′,5′-trimethoxyflavanone 5,7-二羟基-3′,4′,5′-三甲氧基黄烷酮 标准品
| CAS | 62252-10-2 |
| 分子式 | C18H18O7 |
| 分子量 | 346.339996 |
| 储存条件 | Store in dry and dark place. |
| 纯度 | HPLC ≥90% |
| 单位 | 瓶 |
| 货期 | 4周 |
| 规格 | 10mg |
5-Methoxyflavanone 5-甲氧基黄烷酮 标准品
| CAS | 55947-36-9 |
| 分子式 | C16H14O3 |
| 分子量 | 254.289993 |
| 储存条件 | Store in dry and dark place. |
| 纯度 | HPLC ≥90% |
| 单位 | 瓶 |
| 货期 | 4周 |
| 规格 | 20mg |
黄烷酮 标准品
| EC | EINECS 207-654-8 |
| MDL | MFCD00006841 |
| 别名 | 2,3-二氢黄酮;2-Phenyl-chroman-4-one;2,3-Dihydroflavone;2-phenyl-2,3-dihydrochromen-4-one;4-Flavanone; |
| 英文名称 | Flavanone |
| CAS | 487-26-3 |
| 分子式 | C15H12O2 |
| 分子量 | 224.26 |
| 储存条件 | 2-8℃ |
| 纯度 | GC≥98% |
| 单位 | 瓶 |
| SMILES | O=C1CC(C2=CC=CC=C2)OC3=C1C=CC=C3 |
| 规格 | 200mg |
Flavanone 黄烷酮 标准品
| CAS | 487-26-3 |
| 分子式 | C15H12O2 |
| 分子量 | 224.270004 |
| 储存条件 | Store in dry and dark place. |
| 纯度 | HPLC ≥90% |
| 单位 | 瓶 |
| 货期 | 4周 |
| 规格 | 1g |
4′,5,7-三羟基黄烷酮
| 别名 | (±)-柚皮素 |
| 英文名称 | 4′,5,7-Trihydroxyflavanone |
| CAS | 67604-48-2 |
| 分子式 | C15H12O5 |
| 分子量 | 272.269989 |
| 储存条件 | 4℃ |
| 纯度 | HPLC : ≥99% |
| 单位 | 瓶 |
| 货期 | 4周 |
| 规格 | 20mg |
山姜素
| MDL | MFCD00238532 |
| 描述 | 是一种UCK2 抑制剂。 |
| 别名 | 山姜苷;(S)-7-羟基-5-甲氧基黄烷酮 |
| 英文名称 | Alpinetin |
| CAS | 36052-37-6 |
| 分子式 | C16H14O4 |
| 分子量 | 270.28 |
| 纯度 | HPLC≥98% |
| 单位 | 瓶 |
| 生物活性 | Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities.[1-2] |
| In Vitro | Alpinetin markedly inhibits the LPS- induced TNF-α, IL-6 and IL-1β production both in vitro and vivo. Furthermore, alpinetin blocks the phosphorylation of IκBα protein, p65, p38 and extracellular signal-regulated kinase (ERK) in LPS stimulated RAW 264.7 cells[1]. Alpinetin can suppress the proliferation and invasiveness of GSCs and induce apoptosis in GSCs[2]. |
| In Vivo | Alpinetin attenuates lung histopathologic changes in mouse models[1].The anti-tumor activity of alpinetin was further confirmed in an animal model. Collectively, targeting of GSC by alpinetin is an effective strategy for glioma therapy.[2] |
| SMILES | O=C1C[C@@H](C2=CC=CC=C2)OC3=CC(O)=CC(OC)=C13 |
| 靶点 | UCK2 |
| 动物实验 | Cell viability is evaluated by MTT assay. Briefly, 100 μl cells are plated at a density of 4×105 cells/ml in 96-well plates in a 37 ℃, 5% CO2 incubator for 1 h. Then the cells are treated with 50 μl of alpinetin of different concentrations (0-300 μg/ml) for 1 h, followed by stimulation with 50 μl LPS (4 μg/ml). The total volume of each well is 200 μl, and the concentrations of Alpinetin and LPS are four times diluted finally. After 18 h of LPS stimulation, 20 μl MTT (5 mg/ml) is added to each well, and the cells are further incubated for an additional 4 h. The supernatant is removed and the formation of formazan is resolved with 150 μl/well of DMSO. The optical density is measured at 570 nm on a microplate reader.[1] |
| 细胞实验 | Animal Models: Male BALB/c mice; Dosages: 50 mg/kg; Administration: i.p.[1] |
| 数据来源文献 | [1] Huo M, et al. Int Immunopharmacol. 2012, 12(1):241-8. [2] Wang J, et al. Tumour Biol. 2016, 37(7):9243-8. |
| 规格 | 10mg 20mg |
是一种黄酮类化合物，能够活化 PPAR-γ，具有抗炎活性。
Flavanone；黄烷酮
| EC | EINECS 207-654-8 |
| MDL | MFCD00006841 |
| InChIKey | ZONYXWQDUYMKFB-UHFFFAOYSA-N |
| InChI | InChI=1S/C15H12O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-9,15H,10H2 |
| PubChem CID | 10251 |
| 别名 | 2,3-二氢黄酮;2-Phenyl-chroman-4-one;2,3-Dihydroflavone;2-phenyl-2,3-dihydrochromen-4-one;4-Flavanone |
| 英文名称 | Flavanone |
| CAS | 487-26-3 |
| 分子式 | C15H12O2 |
| 分子量 | 224.26 |
| 纯度 | GC≥98% |
| 单位 | 支 |
| SMILES | O=C1CC(C2=CC=CC=C2)OC3=C1C=CC=C3 |
| 靶点 | Others |
| 规格 | 100mg 200mg 500mg |
4′-Methoxyflavanone 4′-甲氧基黄烷酮 标准品
| CAS | 97005-76-0 |
| 分子式 | C16H14O3 |
| 分子量 | 254.289993 |
| 储存条件 | Store in dry and dark place. |
| 纯度 | HPLC ≥95% |
| 单位 | 瓶 |
| 货期 | 4周 |
| 规格 | 20mg |
雌马酚 标准品
| 有效期 | 2年 |
| MDL | MFCD00200962 |
| 别名 | (S)-3,4-二氢-3-(4-羟基苯基)-2H-1-苯并吡喃-7-醇 雌马酚,4′,7-异黄烷二酚; |
| 英文名称 | Equol |
| CAS | 531-95-3 |
| 分子式 | C15H14O3 |
| 分子量 | 242.27 |
| 储存条件 | RT |
| 纯度 | HPLC≥98% |
| 外观（性状） | White to light yellow Powder |
| 单位 | 瓶 |
| 规格 | 10mg |