环吡酮胺
货号：
IC2740
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| EC | EINECS 249-577-2 |
| MDL | MFCD00599441 |
| InChIKey | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
| InChI | InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 |
| PubChem CID | 2749 |
| 别名 | 环匹罗司;环匹罗司胺 |
| 英文名称 | Ciclopirox |
| CAS | 29342-05-0 |
| 分子式 | C12H17NO2 |
| 分子量 | 207.27 |
| 储存条件 | 2-8℃ |
| 纯度 | ≥98% |
| 外观（性状） | White to light yellow Powder |
| 单位 | 瓶 |
| In Vitro | In a study conducted to further elucidate Ciclopirox’s mechanism, several Saccharomyces cerevisiae mutants were screened and tested. Results from interpretation of the effects of both the drug treatment and mutation suggested that Ciclopirox may exert its effect by disrupting DNA repair, cell division signals and structures (mitotic spindles) as well as some elements of intracellular transport[2]. |
| SMILES | CC(C=C(C1CCCCC1)N2O)=CC2=O |
| 靶点 | Fungal |
| 数据来源文献 | [1]. Niewerth, M., et al., Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother, 2003. 47(6): p. 1805-17. [2]. Leem, S.H., et al., The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. Mol Cells, 2003. 15(1): p. 55-61. |
| 规格 | 25mg 50mg 100mg |
是一种抗真菌化合物。