头孢氨苄 标准品
| 英文名称 | Cephalexin monohydrate |
| 分子式 | C16H17N3O4S·H2O |
| 分子量 | 365.41 |
| 储存条件 | 2-8℃ |
| 单位 | 瓶 |
| 规格 | 200mg |
别名：头孢菌素Ⅳ;先锋霉素Ⅳ;苯甘头孢菌素;苯甘孢霉素;头孢氨苄一水合物;(6R,7R)-3-甲基-7-[(R)-2-氨基-2-苯乙酰氨基]-8-氧-5-硫杂-1-双环[4・2・0]辛-2-烯-2-甲酸
头孢氨苄一水 标准品
| EC | EINECS 239-773-6 |
| MDL | MFCD00167148 |
| 别名 | 头孢氨苄单水合物 |
| 英文名称 | Cephalexin |
| CAS | 23325-78-2 |
| 分子式 | C16H17N3O4S·H2O |
| 分子量 | 365.4 |
| 储存条件 | 2-8℃ |
| 纯度 | HPLC≥98% |
| 外观（性状） | 白粉 |
| 单位 | 瓶 |
| SMILES | O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O.O |
| 规格 | 200mg |
头孢氨苄 标准品
| 有效期 | 2 Years |
| EC | EINECS 239-773-6 |
| MDL | MFCD04966776 |
| 别名 | 苯甘头孢霉素 |
| 英文名称 | Cephalexin |
| CAS | 15686-71-2 |
| 分子式 | C16H17N3O4S |
| 分子量 | 347.39 |
| 储存条件 | 2-8℃ |
| 纯度 | HPLC≥98% |
| 外观（性状） | White to pale yellow Powder |
| 单位 | 瓶 |
| SMILES | O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O |
| 规格 | 200mg |
Cephalexin (monohydrate) 头孢氨苄
| MDL | MFCD00167148 |
| EC | EINECS 239-773-6 |
| 别名 | 头孢氨苄 |
| CAS | 23325-78-2 |
| 分子式 | C16H17N3O4S·H2O |
| 分子量 | 365.4 |
| 纯度 | HPLC≥98% |
| 单位 | 瓶 |
| SMILES | O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O.O |
| 靶点 | Bacterial |
| 规格 | 50mg 100mg 500mg |
是头孢菌素类抗生素。
Cefalexin；头孢氨苄
| MDL | MFCD04966776 |
| EC | EINECS 239-773-6 |
| InChIKey | ZAIPMKNFIOOWCQ-UEKVPHQBSA-N |
| InChI | InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 |
| PubChem CID | 27447 |
| 别名 | 苯甘头孢霉素;Sintolexyn |
| 英文名称 | Cefalexin |
| CAS | 15686-71-2 |
| 分子式 | C16H17N3O4S |
| 分子量 | 347.39 |
| 纯度 | ≥98% |
| 单位 | 瓶 |
| 生物活性 | Cephalexin is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall[1-2]. |
| In Vivo | After a single intravenous administration of cephalexin (5 mg/kg), Mate1(-/-) mice showed higher plasma concentrations of cephalexin than wild-type [Mate1(+/+)] mice. The urinary excretion of cephalexin for 60 min was significantly reduced, and the renal concentration was markedly increased in Mate1(-/-) mice compared with Mate1(+/+) mice. The renal clearance of cephalexin in Mate1(-/-) mice was approximately 60% of that in Mate1(+/+) mice and seemed to be near the creatinine clearance.[1] Cephalexin increases the activity of superficial mucous cells and orifice mucous cells of gastric glands, and inhibits the activity of cervix mucous cells. A simultaneous administration of ethanol and cephalexin causes atrophic changes in gastric glands, and thereby strong reduction of mucous cells activity.[2] |
| SMILES | O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O |
| 靶点 | Bacterial |
| 动物实验 | The Wistar rat males weighing approximately 200 g were administered 20% ethanol ad libitum during 10 days, cephalexin in the dose of 42 mg/24 h, and simultaneously ethanol and cephalexin in the above-mentioned doses. After 10 days the animals were decapitated and stomach specimens were taken from the major curvature region for examinations. [2] |
| 数据来源文献 | [1] Watanabe S, et al. J Pharmacol Exp Ther, 2010, 334(2), 651-656. [2] Zarebska A, et al. Ann Univ Mariae Curie Sklodowska Med, 2004, 59(1), 145-150. |
| 规格 | 500mg 1g 5g |
Cefalexin是头孢菌素类抗生素。