溴羟喹啉
货号：
IB2670
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| EC | EINECS 208-317-8 |
| MDL | MFCD00006785 |
| InChIKey | ZDASUJMDVPTNTF-UHFFFAOYSA-N |
| InChI | InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H |
| PubChem CID | 2453 |
| 别名 | 5,7-二溴-8-氧化喹啉 |
| 英文名称 | Broxyquinoline |
| CAS | 521-74-4 |
| 分子式 | C9H5Br2NO |
| 分子量 | 302.95 |
| 储存条件 | -20℃ |
| 纯度 | ≥98% |
| 外观（性状） | White to yellowish green Podwer |
| 单位 | 瓶 |
| 生物活性 | Broxyquinoline (Dibromohydroxyquinoline) is a potent severe fever with thrombocytopenia syndrome virus (SFTSV) inhibitor with an IC50 of 5.8 μM. Broxyquinoline is an antiprotozoal agent[1-2]. |
| In Vitro | Four compounds displayed efficacies against parasite growth in vitro with low micromolar IC(50) values. The effective compounds were broxyquinoline (IC(50) 64.9 μM), cloxyquin (IC(50) 25.1 μM), cloxacillin sodium (IC(50) 36.2 μM) and sodium dehydrocholate (IC(50) 53.2 μM).[2] |
| SMILES | OC1=C2N=CC=CC2=C(Br)C=C1Br |
| 靶点 | Parasite |
| 数据来源文献 | [1]. Shuofeng Yuan, et al. Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus. Viruses. 2019 Apr 25;11(4):385. [2]. Fritzler JM, et al. Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP). J Antimicrob Chemother. 2012 Mar;67(3):609-17. |
| 规格 | 100mg 250mg |
是一种抗原虫化合物。