【简单介绍】
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Recombinant Murine TNF-a，中文名称：重组小鼠肿瘤坏死因子α，规格：20ug，货号：315-01a，Peprotech |
【详细说明】
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Recombinant Murine TNF-a： TNF-alpha is a pleiotrophic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-alpha is a soluble 156 amino acid protein （17.3 kDa） which corresponds to C-terminal extracellular domain of the full length transmembrane protein.  |