TLR5激动剂及相关产品
细胞表面受体TLR5可识别鞭毛蛋白,后者是革兰氏阳性菌和革兰氏阴性菌表面鞭毛丝的主要成份。TLR5活化后通过MyD88信号通路促进一些炎症因子的释放。TLR5通过形成同源二聚体来激活炎症信号通路,这显示它可能是唯一参与鞭毛蛋白识别的TLR分子。
TLR5激动剂产品如下:
PRODUCT |
ORIGIN/DESCRIPTION |
GRADE* |
WORKING CONCENTRATION |
QTY |
CATALOG CODE |
TLR5 Agonists |
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FLA-BS |
Standard flagellin from B. subtilis – 10% pure |
TLR2 + /TLR4 + |
10 ng – 10 µg/ml |
100 µg |
tlrl-bsfla |
FLA-BS Ultrapure |
Ultrapure flagellin from B. subtilis – >95% pure |
TLR2 – /TLR4 – |
1 ng – 1 µg/ml |
50 µg |
tlrl-pbsfla |
FLA-PA Ultrapure |
Ultrapure flagellin from P. aeruginosa – >95% pure |
TLR2 – /TLR4 – |
1 ng – 1 µg/ml |
50 µg |
tlrl-pafla |
FLA-ST |
Standard flagellin from S. typhimurium – 10% pure |
TLR2 + /TLR4 + |
10 ng – 10 µg/ml |
100 µg |
tlrl-stfla |
FLA-ST Ultrapure |
Ultrapure flagellin from S. typhimurium – >95% pure |
TLR2 – /TLR4 – |
10 – 100 ng/ml |
10 µg 50 µg |
tlrl-epstfla tlrl-epstfla-5 |
RecFLA-ST |
Recombinant flagellin from S. typhimurium |
TLR2 – /TLR4 – |
10 – 100 ng/ml |
50 µg 10 µg |
tlrl-flic-50 tlrl-flic-10 |
Flagellin Flic VacciGrade™ |
Preclinical grade RecFLA-ST |
VacciGrade™ |
1 – 10 µg/mouse |
50 µg |
vac-fla |
TLR5 Antagonist |
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hTLR5-Fc |
Soluble ectodomain of TLR5 |
TLR2 – /TLR4 – |
10 ng- 1 µg/ml |
50 µg |
fc-htlr5 |
更多详情请咨询Invivogen代理商-上海金畔生物