Trilink CleanCap® Reagent AG – (N-7113)产品介绍
Trilink CleanCap® Reagent AG – (N-7113)产品介绍
mRNA共转录加帽产品CleanCap® Reagent AG，m7G(5′)ppp(5′)(2’OMeA)pG
产品描述：
CleanCap® Reagent AG是Trilink专利加帽产品，Trilink N-7113体外共转录，5’端加帽形成cap1结构。CleanCap的加帽效率可以达到98%。请注意：Trilink推荐尽可能使用CleanCapAG，CleanCap AG需要AG启动子。通常情况下，CleanCap AG的加帽效率>90%。和CleanCap AG不同，CleanCap GG (cat. no. N-7133 or N-7433) 的专利效率和产量和ARCA类似。
产品信息：
|
产品货号 |
N-7113 |
|
纯度 |
≥95% by AX-HPLC |
|
消光系数 |
30,539 Lmol-1cm-1 at 255 nm |
|
分子式 |
C32H43N15O24P4 (游离酸) |
|
分子质量 |
1145.60 g/mole (游离酸) |
|
盐形式 |
Na+ |
|
浓度 |
100 mM |
|
溶液组分 |
水 |
|
推荐的储存温度 |
-20°C 或者以下 |
|
其他名称 |
CleanCap® Reagent AG for co-transcriptional capping of mRNA,m7G(5′)ppp(5′)(2’OMeA)pG |
|
应用 |
CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases |
|
主链 |
5′-5′-三磷酸 |
|
碱基类似物 |
腺苷酸，鸟苷酸 |
|
核苷酸种类 |
帽类似物 |
产品规格如下：
|
供应商 |
产品编号 |
产品名称 |
规格 |
|
TriLink |
N-7113-1 |
CleanCap Reagent AG, 1 umole |
1 umol |
|
TriLink |
N-7113-10 |
CleanCap Reagent AG, 10 umoles |
10 umol |
|
TriLink |
N-7113-100 |
CleanCap Reagent AG, 100 µmole |
100 umol |
|
TriLink |
N-7113-5 |
CleanCap Reagent AG, 5 umole |
5 umol |
文献引用；
Jiang, T;Henderson, JM;Coote, K;Cheng, Y;Valley, HC;Zhang, XO;Wang, Q;Rhym, LH;Cao, Y;Newby, GA;Bihler, H;Mense, M;Weng, Z;Anderson, DG;McCaffrey, AP;Liu, DR;Xue, W; . Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope
Tusup, M;L . mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma
Yu, D;Kaur, G;Blumenthal, RM;Zhang, X;Cheng, X; . Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima
Dobie?y?ska, A;Miszkiewicz, J;Dar?ynkiewicz, ZM;Tyras, M;Stankiewicz-Drogo?, A;Trylska, J;Dar?ynkiewicz, E;Grzela, R; . Development of bis-ANS-based modified fluorescence titration assay for IFIT/RNA studies
Hashimoto, K;Kodama, A;Ohira, M;Kimoto, M;Nakagawa, R;Usui, Y;Ujihara, Y;Hanashima, A;Mohri, S; . Transient induction of cell cycle promoter Fam64a improves cardiac function through regulating Klf15-dependent cardiomyocyte differentiation in mice
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