Promise proteomics – New catalaog SIL-Proteins 2022
SIL-PROTEINS | |||||||
Promise Proteomics is a pioneer and expert in mass spectrometry-basedquantification methods development and in bioproduction of Stable Isotope Labelled (SIL) proteins |
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Why using our SIL-Protein ? | |||||||
Our SIL-proteins are the gold standard forquantitative LC-MS. | Characteristics | ||||||
SIL-Proteins correct bias occuring duringthe preparation and analytical workflowand due to losses, incomplete digestion,adsorption, proteolysis… With SIL-Proteins,the accuracy and reproducibility of yourquantification data is improved. | ✮ Full length recombinant proteins ✮ Identical to the protein of interest, same sequence as native protein ✮ High isotopic incorporation,stability and purity ✮ Uniform or specific labelling, 13C,15N isotope ✮ Unlabelled option |
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This product is useful for : ✮ Bioanalysis pharmacokinetics studies(clinical & nonclinical), ✮ Research and Discovery/pre-clinical/clinical drug development ✮ Biomarker’s quantification |
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How to use it ? | |||||||
Unlike the use of SIL-peptides, Promise’s SIL-proteins are processed along with thetarget analytes throughout the pre-analytical and LC-MS workflow. |
Human Proteins | Unlabelled | Labelled | |||||
Neuroscience/Psychiatric diseases biomarkers | |||||||
Apolipoprotein E3 | U15N | ||||||
Neurofilament | (Arg,Lys) 13C15N | ||||||
Synuclein alpha | (Arg,Lys) 13C15N | ||||||
Synuclein beta | U15N | ||||||
Synuclein gamma | U15N | ||||||
Tau 441 | (Arg,Lys) 13C15N | ||||||
Tau 352 | U15N | ||||||
Cardiovascular disease biomarkers | |||||||
Apolipoprotein A1 | U15N | ||||||
Carboxypeptidase B2 | (Arg,Lys) 13C15N | ||||||
Clusterin protein | (Arg,Lys) 13C15N | ||||||
NT-proBNP | U15N | ||||||
Troponin I | U15N | ||||||
Metabolic biomarkers | |||||||
Albumin | U15N | ||||||
Cystatin C | U15N | ||||||
Erythropoietin | (Arg,Lys) 13C15N | ||||||
Growth hormone 22 | U15N | ||||||
Vitamin D binding Protein | (Arg,Lys) 13C15N | ||||||
Cancer biomarkers | |||||||
Alpha Feto Protein | (Arg,Lys) 13C15N | ||||||
Choriogonadotropin | (Arg,Lys) 13C15N | ||||||
KRAS 2A | U15N | ||||||
KRAS 2B G12C mutant | (Arg,Lys) 13C15N | ||||||
KRAS 2B G12C/C118A mutant | |||||||
KRAS 2B 12C/C51S/C80L/C118S | |||||||
KRAS 2B G12D mutant | (Arg,Lys) 13C15N | ||||||
KRAS 2B G13C mutant | (Arg,Lys) 13C15N | ||||||
KRAS 2B G13D mutant | (Arg,Lys) 13C15N | ||||||
NRAS | U15N | ||||||
Sepsis biomarker | |||||||
Procalcitonin | U15N |
Human Proteins | Unlabelled | Labelled | |||||
Neuroscience/Psychiatric diseases biomarkers | |||||||
Apolipoprotein E3 | ✔ | U15N | ✔ | ||||
Neurofilament | ✔ | (Arg,Lys) 13C15N | ✔ | ||||
Synuclein alpha | ✔ | (Arg,Lys) 13C15N | ✔ | ||||
Synuclein beta | U15N | ✔ | |||||
Synuclein gamma | U15N | ✔ | |||||
Tau 441 | ✔ | (Arg,Lys) 13C15N | ✔ | ||||
Tau 352 | U15N | ✔ | |||||
Cardiovascular disease biomarkers | |||||||
Apolipoprotein A1 | ✔ | U15N | ✔ | ||||
Carboxypeptidase B2 | (Arg,Lys) 13C15N | ✔ | |||||
Clusterin protein | (Arg,Lys) 13C15N | ✔ | |||||
NT-proBNP | ✔ | U15N | ✔ | ||||
Troponin I | U15N | ✔ | |||||
Metabolic biomarkers | |||||||
Albumin | U15N | ✔ | |||||
Cystatin C | ✔ | U15N | ✔ | ||||
Erythropoietin | (Arg,Lys) 13C15N | ✔ | |||||
Growth hormone 22 | ✔ | U15N | ✔ | ||||
Vitamin D binding Protein | (Arg,Lys) 13C15N | ✔ | |||||
Cancer biomarkers | |||||||
Alpha Feto Protein | (Arg,Lys) 13C15N | ✔ | |||||
Choriogonadotropin | (Arg,Lys) 13C15N | ✔ | |||||
KRAS 2A | ✔ | U15N | ✔ | ||||
KRAS 2B G12C mutant | ✔ | (Arg,Lys) 13C15N | ✔ | ||||
KRAS 2B G12C/C118A mutant | ✔ | ||||||
KRAS 2B 12C/C51S/C80L/C118S | ✔ | ||||||
KRAS 2B G12D mutant | (Arg,Lys) 13C15N | ✔ | |||||
KRAS 2B G13C mutant | (Arg,Lys) 13C15N | ✔ | |||||
KRAS 2B G13D mutant | (Arg,Lys) 13C15N | ✔ | |||||
NRAS | ✔ | U15N | ✔ | ||||
Sepsis biomarker | |||||||
Procalcitonin | ✔ | U15N | ✔ |
PROTEINS | LINK FOR DATASHEET | ||||||
Albumin – Labelled U15N | https://promise-proteomics.com/product/15n-labelled-albumin | ||||||
Alpha Feto Protein – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/alpha-foeto-protein-afp13c15n | ||||||
APO A1 – Labelled U15N | https://promise-proteomics.com/product/vitamin-d-biding-protein-13c15n-2 | ||||||
APO A1 – Unlabelled | https://promise-proteomics.com/product/human-apo-a1-light | ||||||
APO E3 – Labelled U15N | https://promise-proteomics.com/product/vitamin-d-biding-protein-13c15n-2-2 | ||||||
APO E3 – Unlabelled | https://promise-proteomics.com/product/human-apo-eiii-light | ||||||
Carboxypeptidase B2 – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/carboxypeptidase-b2-cpb2-13c15n | ||||||
Choriogonadotropin – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/choriogonadotropin-labelled | ||||||
Clusterin protein – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/human-clusterin-protein-13c15n | ||||||
Cystatin C – Labelled U15N | https://promise-proteomics.com/product/cystatin-c-15n | ||||||
Cystatin C – Unlabelled | https://promise-proteomics.com/product/cystatin-c-light | ||||||
Erythropoietin – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/human-erythropoietin-epo-13c15n | ||||||
Growth hormone 22 – Labelled U15N | https://promise-proteomics.com/product/labelled-growth-hormone-22-u15n | ||||||
Growth Hormone 22 – Unlabelled | https://promise-proteomics.com/product/growth-hormone-22-light | ||||||
KRAS 2B G12C mutant – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/human-kras-13c15n | ||||||
KRAS 2B G12C mutant – Unlabelled | https://promise-proteomics.com/product/human-kras-g12c-mutant-light | ||||||
KRAS 2B G12C/C118A mutant – Unlabelled | https://promise-proteomics.com/product/kras-g12c-c118a-mutant-unlabelled | ||||||
KRAS 2B G12C/C51S/C80L/C118S – Unlabelled | https://promise-proteomics.com/product/kras-2b-g12c-c51s-c80l-c118s-unlabelled | ||||||
Human KRAS 2B G12D mutant – Labelled (Arg, Lys) 13C15N | https://promise-proteomics.com/product/kras-2b-g12d-mutant-labelled-arglys-13c15n | ||||||
Human KRAS 2B G13C mutant – Labelled (Arg, Lys) 13C15N | https://promise-proteomics.com/product/kras-2b-g13c-mutant-labelled-arglys-13c15n | ||||||
KRAS 2B G13D mutant – Labelled (Arg, Lys) 13C15N | https://promise-proteomics.com/product/kras-2b-g13d-mutant-labelled-arglys-13c15n | ||||||
KRAS 2A – Labelled U15N | https://promise-proteomics.com/product/kras-2a-labelled-u15n | ||||||
KRAS 2A – Unlabelled | https://promise-proteomics.com/product/kras-2a-unlabelled | ||||||
NRAS – Labelled U15N | https://promise-proteomics.com/product/nras-labelled-u15n | ||||||
NRAS – Unlabelled | https://promise-proteomics.com/product/nras-unlabelled | ||||||
KRAS 2B – Unlabelled | https://promise-proteomics.com/product/kras-2b-unlabelled | ||||||
Neurofilament – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/vitamin-d-biding-protein-13c15n | ||||||
Neurofilament – Unlabelled | https://promise-proteomics.com/product/human-neurofilament-light | ||||||
NT-proBNP – Labelled U15N | https://promise-proteomics.com/product/nt-probnp-labelled-arglys-13c15n-2 | ||||||
NT-proBNP – Unlabelled | https://promise-proteomics.com/product/nt-probnp-labelled-arglys-13c15n | ||||||
Procalcitonin – Labelled U15N | https://promise-proteomics.com/product/procalcitonin-pct-u15n | ||||||
Procalcitonin – Unlabelled | https://promise-proteomics.com/product/procalcitonin-pct-light | ||||||
Synuclein alpha – Labelled (Lys) 13C15N | https://promise-proteomics.com/product/synuclein-13c15n | ||||||
Synuclein alpha – Unlabelled | https://promise-proteomics.com/product/synuclein-light | ||||||
Synuclein beta – Labelled U15N | https://promise-proteomics.com/product/synuclein-beta-labelled-u15n | ||||||
Synuclein gamma – Labelled U15N | https://promise-proteomics.com/product/synuclein-gamma-labelled-u15n | ||||||
Tau 441 – Labelled (Arg,Lys) 13C15N | https://promise-proteomics.com/product/tau-13c15n | ||||||
Tau 441 – Unlabelled | https://promise-proteomics.com/product/tau-light | ||||||
Tau 352- Labelled U15N | https://promise-proteomics.com/product/tau-352-labelled-u15n | ||||||
Troponin I – Labelled U15N | https://promise-proteomics.com/product/human-troponin-i-15n | ||||||
Vitamin D binding Protein -Labelled (Arg, Lys) 13C15N | https://promise-proteomics.com/product/human-kras-13c15n-2 |
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