Co 101244 hydrochlorideCAS号： 193356-17-1分子式： C21H28ClNO3分子量： 377.90描述纯度储存/保存方法别名可溶性/溶解性In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
Co 101244 (PD 174494) hydrochloride is a NR2B-containing NMDA receptor antagonist.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 别名 |
PD 174494 hydrochloride
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| 可溶性/溶解性 |
DMSO
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| 生物活性 | |
| In vitro(体外研究) |
Co 101244 effectively reduces NMDA-evoked Ca2+ elevations while enhancing neuroprotection.
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| In vivo(体内研究) |
Co 101244 (0.1, 1 mg/kg s.c.) displayed antidyskinetic effects (67 and 71% reduction, respectively) while sparing levodopa motor benefit.
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分子结构图
