原苏木素B
货号：
IP3510
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| MDL | MFCD20527297 |
| 别名 | 原巴西苏木素 |
| 英文名称 | Protosappanin B |
| CAS | 102036-29-3 |
| 分子式 | C16H16O6 |
| 分子量 | 304.29 |
| 储存条件 | 2-8℃ |
| 纯度 | ≥98% |
| 外观（性状） | White to off-white (Solid) |
| 单位 | 瓶 |
| 生物活性 | Protosappanin B is a phenolic compound extracted from Lignum Sappan. Anti-cancer activity[1]. Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells[2]. |
| In Vitro | Protosappanin B (12.5, 25, 50, 100, 200 μg/mL, 48 hours) dose-dependently inhibits tumor cells, with IC50s of 21.32 μg/mL, 26.73 μg/mL, and 76.53 μg/mL for SW-480, HCT-116, and BTT cells, respectively[1]. |
| SMILES | OC1=CC=C2C(OC[C@@](O)(CO)CC3=CC(O)=C(O)C=C23)=C1 |
| 靶点 | Others |
| 数据来源文献 | [1]. Yang X, et al. Antitumor Effects of Purified Protosappanin B Extracted From Lignum Sappan. Integr Cancer Ther. 2016 Mar;15(1):87-95.
[2]. Yang X, et al. Protosappanin B promotes apoptosis and causes G1 cell cycle arrest in human bladder cancer cells. Sci Rep. 2019 Jan 31;9(1):1048 |
| 规格 | 5mg 10mg |
Protosappanin B 是一种多酚类物质，具有抗肿瘤活性。