Rabbit anti-Antithrombin III Recombinant Monoclonal Antibody(294-211)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明细胞定位UniProt
| 概述 | |
| 别名 |
ATIII; Serpin C1
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
WB: 1:1000
|
| 免疫原 |
Recombinant protein
|
| 性能 | |
| 形式 |
Liquid
|
| 浓度 |
0.5 mg/mL
|
| 纯化方法 |
Protein A affinity column
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
294-211
|
| 储存/保存方法 |
Store at -20℃ for one year.
|
| 存储溶液 |
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
|
| 靶标 | |
| 背景说明 |
Antithrombin III (AT III) is primarily a potent anticoagulant with independent anti-inflammatory properties. AT III irreversibly inhibits serine proteases (e.g. activated factor X and thrombin) in a one-to-one ratio, with the generation of protease–AT III complexes. Heparin prevents AT III from interacting with the endothelial cell surface by binding to sites on the AT III molecule, competing for the AT III binding site, and reducing AT III’s ability to interact with its cellular receptor [PMID: 26862016].
|
| 细胞定位 |
Secreted, Extracellular space
|
| UniProt |
P01008
|
实验结果图
WB result of Antithrombin III Rabbit mAb Primary antibody: Antithrombin III Rabbit mAb at 1/1000 dilution Lane 1: Human serum lysate 20 µg Secondary antibody: #JP20040 at 1/10000 dilution Predicted MW: 52kDa Observed MW: 55kDa Exposure time: 180s