NSC 624206CAS号： 13116-77-3分子式： C19H32ClNS2 • HCl分子量： 410.5描述纯度储存/保存方法别名外观可溶性/溶解性参考文献
| 产品描述 | |
| 描述 |
NSC 624206 is an inhibitor of ubiquitin-activating enzyme (E1) that specifically blocks ubiquitin-thioester formation (IC50 = 13 µM) but has no effect on ubiquitin adenylation. Through this action, NSC 624206 prevents the ubiquitination and degradation of the tumor suppressor protein p27 in vitro. |
| 纯度 |
≥95%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
N-(3-(4-chlorophenyl)-3,3-dimercaptopropyl)decan-1-aminium chloride
|
| 外观 |
solid
|
| 可溶性/溶解性 |
Soluble in DMSO
|
| 参考文献 | |
| 参考文献 |
1.Ungermannova, D.,Parker, P.J.,Nasveschuk, C.G., et al. Identification and mechanistic studies of a novel ubiquitin E1 inhibitor. J. Biomol. Screen. 17(4), 421-434 (2012).
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分子结构图
